Senior Scientist, Biochemistry, Enzymology, Biophysics - Springhouse, PA.
Company: Johnson & Johnson
Location: Spring House
Posted on: January 16, 2022
Janssen Research & Development, L.L.C., a Johnson & Johnson
company, is recruiting for a Senior Scientist, Biochemistry,
Enzymology, Biophysics for the Molecular and Cellular Pharmacology
team, located in Spring House, PA.
At the Janssen Pharmaceutical Companies of Johnson & Johnson, we
are working to create a world without disease. Transforming lives
by finding new and better ways to prevent, intercept, treat and
cure disease inspires us. We bring together the best minds and
pursue the most promising science.
We are Janssen. We collaborate with the world for the health of
everyone in it. Learn more at www.janssen.com and follow us
@JanssenGlobal. Janssen Research & Development, LLC is part of the
Janssen Pharmaceutical Companies.
Janssen has formed a global multidisciplinary Targeted Protein
Degradation group across all five Janssen Therapeutic Area (TA)
discovery teams. The TPD group mission requires deep scientific
expertise in various disciplines including biochemistry,
enzymology, biophysics, molecular and cellular pharmacology, and
screening technologies coupled with an ability to work
collaboratively with internal and external partners. Building on a
strong legacy of success, we are currently seeking an outstanding
enzymologist/biochemist/biophysicist to join our team as a Senior
Scientist, Biochemistry, Enzymology, Biophysics.
The candidate will be a key member of the Targeted Protein
Degradation team within the Molecular and Cellular Pharmacology
group at Janssen, and provide biochemistry/enzymology/biophysics
support and expertise to therapeutic area programs from target
nomination through declaration of a clinical candidate. S/he should
be an agile learner and innovative problem solver who is capable of
multi-tasking in a fast paced and collaborative environment.
In This Exciting Role, You Will
Employ a combination of scientific tools and methodologies in
mechanistic biochemistry/enzymology/biophysics including reagent
validation, binding and activity assay development, ligand-target
mechanism of action studies, and compound profiling.
Develop and execute target relevant, fit for purpose
biochemical/biophysical/enzymatic assays to support hit triage and
progression of candidate quality molecules
Provide enzymology/biophysics expertise to internal programs as
well as external collaborations.
Explore novel technologies
Collaborate across multiple therapeutic teams and functional areas
in the US, Europe and Asia.
Provide a sense of urgency to deliver data within agreed
Publish research in high-quality journals
PhD is required
Postdoctoral experience is preferred
At least 3 or more years of industry related experience in
enzymology/biochemistry/biophysics/pharmacology or related is
Proven experience and knowledge in biochemistry, enzymology, assay
development, and/or mechanism of action studies is required
Expertise in enzymology with a proven track record of using
steady-state, pre-steady state, and mechanism of action studies to
fully characterize target-ligand interactions is preferred
Strong background in biophysics, protein biochemistry, and assay
development is required
Hands-on experience in direct binding studies like SPR, ITC, or MST
Excellent analytical skills and the ability to analyze and
interpret complex data sets is required
Experience in leading projects independently is preferred
Experience in HTS and automation is preferred
Cellular assay experience is preferred
Johnson & Johnson is an Affirmative Action and Equal Opportunity
Employer. All qualified applicants will receive consideration for
employment without regard to race, color, religion, sex, sexual
orientation, gender identity, age, national origin, or protected
veteran status and will not be discriminated against on the basis
United States-Pennsylvania-Spring House-Welsh & McKean Roads
Janssen Research & Development, LLC (6084)
Keywords: Johnson & Johnson, Philadelphia , Senior Scientist, Biochemistry, Enzymology, Biophysics - Springhouse, PA., Other , Spring House, Pennsylvania
Didn't find what you're looking for? Search again!