Senior Scientist - Cheminformatics - Spring House, PA - (Multiple Openings).
Company: Johnson & Johnson
Location: Spring House
Posted on: January 16, 2022
Janssen Research & Development, L.L.C., a division of Johnson &
Johnson's Family of Companies, is recruiting for a Senior
Scientist, Cheminformatics located in Spring House, PA
At the Janssen Pharmaceutical Companies of Johnson & Johnson, we
are working to create a world without disease. Transforming lives
by finding new and better ways to prevent, intercept, treat and
cure disease inspires us. We bring together the best minds and
pursue the most promising science.
We are Janssen. We collaborate with the world for the health of
everyone in it. Learn more at www.janssen.com and follow us
@JanssenGlobal. Janssen Research & Development, LLC is part of the
Janssen Pharmaceutical Companies.
The Discovery Sciences organization within Janssen R&D is
continuing to build key scientific expertise in screening,
pharmacology and chemistry to partner closely with therapeutic area
scientists to develop groundbreaking new medicines in the areas of
Oncology, Immunology, Neuroscience, Cardiovascular, and Infectious
Diseases. We are seeking excellent drug discovery scientists to
join the team to bring their expertise to exciting efforts in novel
areas of drug discovery.
We are seeking a creative individual with a strong background in
cheminformatics and data science to join the Computational
Chemistry group at Janssen. This person will be responsible for
exploration in a broad range of cheminformatics areas, including
automation integration, high throughput experimentation (HTE) and
DNA-encoded library (DEL) data capture and interpretation, peptide
discovery platform informatics, and high-throughput screening data
As a Senior Scientist in the Computational Chemistry group, you
Enable compound design, synthesis, purification, data analysis,
visualization and decision support for parallel synthesis, high
throughput experimentation (HTE), DNA-encoded library (DEL)
synthesis and screening, and affinity selection (ASMS).
Annotate and assess the success rates of screening platforms and
Closely collaborate with other teams within Janssen, including
computational chemists, ML/AI scientists, IT, medicinal chemists,
and focused chemistry and biology discovery technology groups.
Develop multidimensional data visualizations to allow
interpretation and structure of complex data from multiple internal
and external sources into a format usable by project teams.
PhD in chemistry, computer science, or a related field and at least
3 years of pharmaceutical industry experience is required, or a MS
degree in chemistry, computer science, or a related field with at
least 14 years of pharmaceutical industry experience is
Extensive hands-on experience in cheminformatics (ie. chemical
descriptors, similarity, diversity, SAR analysis, properties,
library enumeration, design, chemical transformations, etc.) with
proven track record of accomplishments is required.
Proficiency with one or more programming, scripting, or querying
languages is required. Examples may include Python, Jupyter
Notebooks, Java, Pipeline Pilot, or SQL.
Expertise in large scale data handling is preferred.
Expertise in generating data visualizations in tools like Spotfire,
Vortex, Tableau, DataWarrior is preferred.
Familiarity with computational chemistry approaches such as
molecular modelling, docking, pharmacophore analysis is
Excellent written and oral communication skills are required.
This position is located in Spring House, PA (Philadelphia area)
and may require approximately 10% travel.
Johnson & Johnson is an Affirmative Action and Equal Opportunity
Employer. All qualified applicants will receive consideration for
employment without regard to race, color, religion, sex, sexual
orientation, gender identity, age, national origin, or protected
veteran status and will not be discriminated against on the basis
United States-Pennsylvania-Spring House-Welsh & McKean Roads
Janssen Research & Development, LLC (6084)
Keywords: Johnson & Johnson, Philadelphia , Senior Scientist - Cheminformatics - Spring House, PA - (Multiple Openings)., Other , Spring House, Pennsylvania
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