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Executive Director, Global Molecule Lead, Neuroscience

Company: Jazz Pharmaceuticals
Location: Philadelphia
Posted on: October 14, 2021

Job Description:

Jazz Pharmaceuticals plc (NASDAQ: JAZZ) is a global biopharmaceutical company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines and novel product candidates, from early- to late-stage development, in neuroscience and oncology. We actively explore new options for patients including novel compounds, small molecules and biologics, and through cannabinoid science and innovative delivery technologies. Jazz is headquartered in Dublin, Ireland and has employees around the globe, serving patients in nearly 75 countries. For more information, please visit and follow @JazzPharma on Twitter.

Jazz Pharmaceuticals is an international biopharmaceutical company focused on improving patients’ lives by identifying, developing and commercializing meaningful products that address unmet medical needs. We are continuing to expand our commercial product portfolio and our research and development pipeline in therapeutic areas that can leverage our unique expertise.

Our therapeutic areas of focus include neuroscience and oncology areas in which we have a deep understanding of the patient journey and a suite of products and product candidates to address critical needs.

We are looking for the best and brightest talent to join our team.  If you’re looking to be a part of a company with an unwavering commitment to improving patients’ lives and being a great place to work, we hope you’ll explore our career openings and get to know Jazz Pharmaceuticals. 


The Global Molecule Lead (GML) is a critical role in the organization that has a significant impact on a molecule or franchise of molecules at all stages of the product lifecycle.  The GML is accountable to the Portfolio Governance Committee (PGC) and the Operating Executive Committee (OEC) for the establishment and execution of a global molecule(s) strategy which integrates scientific rationale, clinical development, regulatory, commercial and CMC strategy, and a global neuroscience franchise plan that optimizes value and is aligned with corporate business objectives.  The GML provides strategic leadership to one or more Global Molecule Team (GMT), and partners with functional area leaders to ensure that the team has necessary resources (per the operating plan) and capabilities to execute on the approved global molecule strategy.  GMLs are part of the cross-functional Franchise Team and members of the Global Product Strategy Department.

Preferred qualifications for this position include: being a strong executive with superior cross-functional collaboration skills, highly effective influencing skills and the ability to operate across multiple geographies.  Must have proven experience leading highly complex and/or high priorities projects.  Success in this critical role will provide the opportunity for significant professional growth.

Key Responsibilities:

  • Serve as the leader of one or more cross-functional Global Molecule Team with accountability for molecule strategy and team leadership throughout the molecule lifecycle
  • Establish a vision and long-term strategy for the molecule or franchise of molecules with the GMT, sub-teams and project teams that are aligned with corporate business objectives
  • Lead GMT’s identification and prioritization of new opportunities, build cross-functional global development plans and navigate internal governance
  • Drive team accountability and effectiveness by setting clear expectations for the GMT and team member’s roles and responsibilities, promoting team cohesiveness to optimize performance, and mediating conflict resolution
  • Provide strategic guidance and support to GMT sub-team projects and activities that are executed in matrix and functional channels (e.g. clinical development, technical operations, commercial, regulatory)
  • Mobilize and align the organization to execute on the approved molecule strategy, including coordination and synchronizing activities with other GMLs and/or GMTs
  • Leverage input from all critical functions to identify and evaluate strategic global product development opportunities that maximize the value of the molecule or franchise of molecules through optimal balance of risk, timelines, cost and revenues
  • Participate in the Long Range Plan (LRP) process and approve underlying assumptions resulting in articulate strategies and plans that align with Jazz mission and approach
  • Make recommendations to Portfolio Governance Committee (PGC) and to the Operating Executive Committee (OEC) to maximize the value of the asset over its entire lifecycle (as captured in the Annual Lifecycle Plan, Product Development Plans, Corporate or Therapeutic Area Strategic Plans)
  • Identify what decisions are at the molecule, portfolio, functional or geographical levels
  • Summarize and communicate key updates, issues, considerations and decision points to PGC and the OEC and other review/decision-making committees
  • May be required to take on additional responsibility for external collaborations and/or corporate strategic projects with high visibility and expanded team leadership responsibilities
    • Collaborate with functional heads in the selection of key GMT members
  • Provide performance review input for key positions on the GMT
  • Partner with relevant functions to develop effective working relationships both internally and with external key stakeholders (development partners, key opinion leaders, advocacy groups, etc.)
  • As appropriate, participate in ongoing development and enhancement of cross-functional team structures, processes, systems, other tools and resources


  • 15+ years multi-disciplinary experience in the pharma/biotech industry
  • Experience as a leader or co-leader (GML, Product Team Lead, General Manager) for a sufficient amount of time to have contributed to a significant milestone (i.e. Phase 3 implementation, major regulatory submission, launch)
  • Bachelor’s degree required, advanced degree (PhD, MBA, MD, PharmD) preferred
  • Neuroscience experience preferred
  • Proven experience as a successful, decisive leader in a strategic multi-functional environment
  • Strong track-record of delivering results through effective team and peer leadership
  • Ability to lead multiple highly complex and/or high priority projects with ambitious milestones in high pressure circumstances
  • Experience at managing  collaborations, alliances or other relationships through influencing without direct authority
  • Proven skills leading in a highly-matrixed environment
  • Ability to synthesize different points of view to make sound, timely and objective decisions
  • Excellent communication skills, including executive presence and strong presentation skills
  • Global role experience and familiarity with US, EU and RoW market dynamics

Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law.

Keywords: Jazz Pharmaceuticals, Philadelphia , Executive Director, Global Molecule Lead, Neuroscience, Other , Philadelphia, Pennsylvania

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