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Scientific Director, Neuroscience Discovery - Neurodegeneration

Company: Disability Solutions
Location: Spring House
Posted on: May 11, 2024

Job Description:

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at . Johnson & Johnson (J&J) is recruiting for a Scientific Director to join our Neuroscience Discovery group based in either Springhouse, PA, USA or Beerse, Belgium. The role will require the candidate to work across time zones as we are a global organization. In the role of Scientific Director, you will lead a team that supports innovative platforms e.g., complex IPSC cellular models of disease and high content imaging to identify novel targets and validate them sufficiently to enter the Neuroscience Discovery Portfolio. You will work closely with our Data Science colleagues to leverage large data sets e.g. proteomics and transcriptomics, as well as genetic and real-world evidence data to shape the discovery portfolio. Your group will be instrumental for us to continue building a transformational Neuroscience portfolio to develop novel treatments for Neurodegenerative and Neuropsychiatric Diseases. This will require excellent communication and teamwork skills, an appetite for innovation, and a keen attention to detail and organization. You should have a considerable sense of purpose and drive, be mindful of the considerable unmet medical need and imperative to generate impactful therapeutics in Neuroscience and embody the critical importance of translation of insights from biology and data science to the vision and mission of Johnson & Johnson. Your Key Responsibilities:

  • Identifying and validating novel druggable targets for the treatment of Neuropsychiatric and Neurodegenerative diseases that are aligned with our Disease Area Strategy using complex human cell models of neuropsychiatric and neurodegenerative disease.
  • Collaborating closely within the Global Biology function and with other functions, including but not limited to, Data Sciences, Discovery Technology & Molecular Pharmacology and In Silico Discovery to integrate data from human cell models, human omics data, and other datasets coupled to AI and machine learning.
  • Build and mentor a highly motivated team that delivers well-defined objectives.
  • Effective oral and written communication to ensure alignment across functions and within the neuroscience department.
  • Maintains a high degree of understanding of external environment including:
    • approaches to accelerate drug development using high dimensionality data (e.g., high content imaging, transcriptomics and proteomics data) combined with advanced analytics.
    • value of human data in precision drug development including molecular datasets and human cell models
    • This position will typically have 1-2 direct reports.

Keywords: Disability Solutions, Philadelphia , Scientific Director, Neuroscience Discovery - Neurodegeneration, Executive , Spring House, Pennsylvania

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