Associate Director, Discovery
Company: LARIMAR THERAPEUTICS INC
Posted on: August 3, 2020
Larimar Therapeutics (formerly Chondrial Therapeutics), based in
the Philadelphia area, is committed to discovering and developing
treatments for complex rare diseases, with an initial focus on
Friedreich's ataxia. Its proprietary protein replacement therapy
platform is intended to deliver missing proteins inside the
machinery of cells to treat devastating rare diseases that
currently have ineffective or no treatments available.
The Associate Director, Discovery will be responsible for the
design and execution of all activities related to drug discovery.
The scientist in this role will report to the VP of Discovery &
Non-Clinical R&D and spearhead the design and implementation of
the company's research connected to early discovery and pipeline
Will include but are not limited to:
--- Manage a multidisciplinary discovery biology team supporting
multiple activities ranging from target identification and
validation and hit identification through clinical candidate
--- Oversee activities from the internal research team, external
partners and consultants to effectively manage projects lifecycle
and support key milestone decisions.
--- Ensure high quality data delivery within timelines and provide
data interpretation for study reports consistent with current
industry and health authority expectations.
--- Ensure effective research collaboration with internal and
external development teams to support translation of
pharmacodynamic and pharmacokinetic endpoints from discovery
studies to regulated toxicology and clinical studies
--- Partner effectively and functions as key contact with internal
stakeholders (Analytical, CMC, Clinical and Regulatory) to ensure
integration of discovery with other company goals.
--- Provide input to the leadership team on discovery pipeline
progression to support strategic planning and budgeting for novel
--- Contribute relevant pharmacological sections to regulatory and
submission documents as needed.
Education, Experience, Skills and Knowledge:
Requires a Ph.D. in Physiology, Biochemistry or a related field
with a minimum of 6-8 years of direct supervisory experience of
early discovery programs in a biotechnology or pharmaceutical
company. The successful candidate will have a demonstrated
expertise managing internal discovery projects in a matrixed
environment, with experience in biotherapeutics development
preferred. Demonstrated ability to assist with the design,
execution and troubleshooting of experiments across a variety of
platforms and strong knowledge of the entire drug development
process is also required. Excellent interpersonal communication
skills are essential to effectively communicate the needs of the
company's programs to external collaborators as well as different
stakeholders within the company.
Equal Opportunity Employment
We are committed to equal-employment principles, and we recognize
the value of committed employees who feel they are being treated in
an equitable and professional manner. We strive to find ways to
attract, develop and retain the talent needed to meet business
objectives, and to recruit and employ highly qualified individuals
representing the diverse communities in which we live.
Employment policies and decisions on employment and promotion are
based on merit, qualifications, performance, and business needs.
The decisions and criteria governing the employment relationship
with all employees are made in a non-discriminatory manner-without
regard to age, race, color, national origin, gender (including
pregnancy, childbirth or medical condition related to pregnancy or
childbirth), gender identity or expression, religion, physical or
mental disability, medical condition, legally protected genetic
information, marital status, veteran status, military status,
sexual orientation, or any other factor determined to be an
unlawful basis for such decisions by federal, state, or local
Keywords: LARIMAR THERAPEUTICS INC, Philadelphia , Associate Director, Discovery, Executive , Philadelphia, Pennsylvania
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