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Proteomics Scientist, Cell Engineering

Company: Disability Solutions
Location: Spring House
Posted on: June 4, 2024

Job Description:

Johnson & Johnson is recruiting a Proteomics Scientist, Cell Engineering located in Spring House, PA. At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at The Cell Engineering & Analytical Sciences group within biologics development is seeking a highly skilled and motivated Proteomics Scientist to join our research and development team. You will play a crucial role in understanding cellular pathways and networks for optimizing recombinant protein production in engineered cell lines, using data-driven systems biology approaches. We are a pioneering mass spectrometry laboratory, equipped with over a dozen instruments, robotic workbenches for sample automation and powerful bioinformatic software and cloud computing resources for data interpretation. We work in an exciting, interdisciplinary environment and collaborate with multi-functional teams, including cell line development and cell culture process development, to provide expert guidance on proteomics-related aspects of cellular expression. Your expertise in protein analysis techniques will help drive the advancement of our biopharmaceutical pipeline. Key Responsibilities:

  • Develop and implement proteomics strategies to support CHO cell engineering of complex biotherapeutic modalities. With the aim of optimizing protein expression levels, protein quality, and glycosylation patterns.
  • Apply sophisticated liquid chromatography-mass spectrometry (LC-MS/MS) for protein identification, quantification, and post-translational modification analysis.
  • Use biostatistics and bioinformatics algorithms to integrate multiple levels of biological information together with proteomics data, for new hypothesis generation,
  • Troubleshoot technical issues and propose innovative solutions to enhance analytical capabilities.
  • Stay up to date with the latest advancements in proteomics and cell engineering, develop new methods and publish in peer reviewed journals.
  • Prepare and present scientific findings and recommendations to internal stakeholders, project teams, and senior management.

Keywords: Disability Solutions, Philadelphia , Proteomics Scientist, Cell Engineering, Engineering , Spring House, Pennsylvania

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